内容紹介
Effectiveness of Skin Icing for Reducing Pain Associated with Luteinizing Hormone-Releasing Hormone Agonist Injection
Summary
We evaluated the effect of using the cooling method on pain at the site of luteinizing hormone-releasing hormone(LH-RH)agonist injection in 181 prostate cancer or premenopausal breast cancer patients by using a numerical rating scale(NRS)and a questionnaire survey with open-ended questions. According to the NRS, 38.1% of the patients experienced a reduction in pain, 37.5% experienced no change, and 24.4% experienced an increase in pain. Therefore, use of the cooling method did not have a statistically significant effect in terms of pain reduction(p=0.123). However, on analyzing pain reduction according to the answers in the questionnaire survey, 53.2% of the patients experienced a reduction in pain, 38.5% experienced no change, and 8.3% experienced an increase in pain. These findings were different from those obtained on using the NRS. In addition, irrespective of using the cooling method, needle thickness and patient obesity strongly influenced the pain experienced. The skin icing method was effective in reducing pain at the site of LH-RH agonist injection. This method is simple, inexpensive, and safe, and is hence recommended.
要旨
前立腺癌あるいは閉経前乳癌患者181例を対象とし,LH-RHアゴニスト投与時の痛みに対する冷却法の効果をnumerical rating scale(NRS)とフリーコメントによるアンケート調査で評価した。冷却法を用いた除痛効果は,NRSでは改善38.1%,不変37.5%,増悪24.4%であり,統計学的な有意差には至らなかった(p=0.123)。しかし,フリーコメントによる除痛効果は,改善53.2%,不変38.5%,増悪8.3%とかなり高く,NRSでの評価と乖離した結果となった。また,冷却法の有無にかかわらず,使用製剤の針の太さや肥満が痛みに強く影響した。冷却法はLH-RHアゴニストの除痛に有効であった。簡便,安価で安全であり,積極的に行っていくべき手技であると考えられた。
目次
Summary
We evaluated the effect of using the cooling method on pain at the site of luteinizing hormone-releasing hormone(LH-RH)agonist injection in 181 prostate cancer or premenopausal breast cancer patients by using a numerical rating scale(NRS)and a questionnaire survey with open-ended questions. According to the NRS, 38.1% of the patients experienced a reduction in pain, 37.5% experienced no change, and 24.4% experienced an increase in pain. Therefore, use of the cooling method did not have a statistically significant effect in terms of pain reduction(p=0.123). However, on analyzing pain reduction according to the answers in the questionnaire survey, 53.2% of the patients experienced a reduction in pain, 38.5% experienced no change, and 8.3% experienced an increase in pain. These findings were different from those obtained on using the NRS. In addition, irrespective of using the cooling method, needle thickness and patient obesity strongly influenced the pain experienced. The skin icing method was effective in reducing pain at the site of LH-RH agonist injection. This method is simple, inexpensive, and safe, and is hence recommended.
要旨
前立腺癌あるいは閉経前乳癌患者181例を対象とし,LH-RHアゴニスト投与時の痛みに対する冷却法の効果をnumerical rating scale(NRS)とフリーコメントによるアンケート調査で評価した。冷却法を用いた除痛効果は,NRSでは改善38.1%,不変37.5%,増悪24.4%であり,統計学的な有意差には至らなかった(p=0.123)。しかし,フリーコメントによる除痛効果は,改善53.2%,不変38.5%,増悪8.3%とかなり高く,NRSでの評価と乖離した結果となった。また,冷却法の有無にかかわらず,使用製剤の針の太さや肥満が痛みに強く影響した。冷却法はLH-RHアゴニストの除痛に有効であった。簡便,安価で安全であり,積極的に行っていくべき手技であると考えられた。