内容紹介
A Case of Triple-Negative Breast Cancer Responding to Multidisciplinary Treatment Containing Bevacizumab
Summary
We report a case of a 64-year-old woman with StageⅣ breast cancer who responded well to chemotherapy containing bevacizumab. She noticed a left breast tumor with acute progression and was diagnosed as having StageⅣ, estrogen receptor(ER)(-), progesterone receptor(PgR)(-), human epidermal growth factor receptor 2(HER2)(-)breast cancer(T4cN3cM1[lymph nodes]). She received 5 courses of adriamycin(60 mg/m2)plus cyclophosphamide(600 mg/m2)(AC therapy)and 4 courses of weekly paclitaxel(PTX 90 mg/m2)plus bevacizumab(AVA 10 mg/m2)as systemic therapy. Computed tomography(CT)and magnetic resonance imaging(MRI)revealed a complete response(CR). After local resection of the breast tumor and radiation to the breast and regional lymph nodes, capecitabine therapy was initiated. Currently, at 5 months after surgery, no new lesion has been detected.
要旨
症例は64歳,女性。急速に増大する乳房腫瘤を主訴に当科受診し,左乳癌T4cN3cM1(LYM),StageⅣ,ER(-),PgR(-),HER2(-)と診断された。AC(adriamycin 60 mg/m2+cyclophosphamide 600 mg/m2)療法5コース,wPTX+AVA(paclitaxel 90 mg/m2+bevacizumab 10 mg/m2)療法4コースを行い画像的にCR。乳房部分切除術と乳房,リンパ節領域のRTの後にcapecitabine内服中であるが,手術後5か月経過の現在,病巣の出現を認めていない。急激な進行を示したStageⅣ乳癌に対してbevacizumabを含む化学療法が有効であった1例を経験したので報告する。
目次
Summary
We report a case of a 64-year-old woman with StageⅣ breast cancer who responded well to chemotherapy containing bevacizumab. She noticed a left breast tumor with acute progression and was diagnosed as having StageⅣ, estrogen receptor(ER)(-), progesterone receptor(PgR)(-), human epidermal growth factor receptor 2(HER2)(-)breast cancer(T4cN3cM1[lymph nodes]). She received 5 courses of adriamycin(60 mg/m2)plus cyclophosphamide(600 mg/m2)(AC therapy)and 4 courses of weekly paclitaxel(PTX 90 mg/m2)plus bevacizumab(AVA 10 mg/m2)as systemic therapy. Computed tomography(CT)and magnetic resonance imaging(MRI)revealed a complete response(CR). After local resection of the breast tumor and radiation to the breast and regional lymph nodes, capecitabine therapy was initiated. Currently, at 5 months after surgery, no new lesion has been detected.
要旨
症例は64歳,女性。急速に増大する乳房腫瘤を主訴に当科受診し,左乳癌T4cN3cM1(LYM),StageⅣ,ER(-),PgR(-),HER2(-)と診断された。AC(adriamycin 60 mg/m2+cyclophosphamide 600 mg/m2)療法5コース,wPTX+AVA(paclitaxel 90 mg/m2+bevacizumab 10 mg/m2)療法4コースを行い画像的にCR。乳房部分切除術と乳房,リンパ節領域のRTの後にcapecitabine内服中であるが,手術後5か月経過の現在,病巣の出現を認めていない。急激な進行を示したStageⅣ乳癌に対してbevacizumabを含む化学療法が有効であった1例を経験したので報告する。