内容紹介
Neutropenic Enterocolitis after Autologous Peripheral Blood Stem Cell Transplantation in Non-Hodgkin's Lymphoma―A Case Report
Summary
Here we report a case of a 59-year-old man who developed neutropenic enterocolitis(NE)after autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma in his second complete remission. Four days after transplantation, the patient suffered from diarrhea, abdominal pain, fever, and paralytic ileus. Abdominal computerized tomography scan revealed bowel wall thickening consistent with NE. Owing to his poor performance status, only medical management, including antibiotics and bowel rest, was administered, and the patient died 18 days after transplantation. Although NE after autologous peripheral blood stem cell transplantation is a relatively rare complication, it is important to be aware that this condition can occur as one of the early complications in stem cell transplantation.
要旨
症例は59歳,男性。第二寛解期の非Hodgkinリンパ腫に対して自家末梢血幹細胞移植を実施した。移植後day +4より下痢,腹痛,発熱および麻痺性イレウスを合併し,CT所見も含めてneutropenic enterocolitis(NE)と診断した。全身状態悪化のため抗生剤投与,絶食を中心とした保存的治療を行ったがday +18に永眠された。移植後のNEは造血幹細胞移植の合併症として比較的まれであるが,早期合併症の一つとして留意すべきである。
目次
Summary
Here we report a case of a 59-year-old man who developed neutropenic enterocolitis(NE)after autologous peripheral blood stem cell transplantation for non-Hodgkin's lymphoma in his second complete remission. Four days after transplantation, the patient suffered from diarrhea, abdominal pain, fever, and paralytic ileus. Abdominal computerized tomography scan revealed bowel wall thickening consistent with NE. Owing to his poor performance status, only medical management, including antibiotics and bowel rest, was administered, and the patient died 18 days after transplantation. Although NE after autologous peripheral blood stem cell transplantation is a relatively rare complication, it is important to be aware that this condition can occur as one of the early complications in stem cell transplantation.
要旨
症例は59歳,男性。第二寛解期の非Hodgkinリンパ腫に対して自家末梢血幹細胞移植を実施した。移植後day +4より下痢,腹痛,発熱および麻痺性イレウスを合併し,CT所見も含めてneutropenic enterocolitis(NE)と診断した。全身状態悪化のため抗生剤投与,絶食を中心とした保存的治療を行ったがday +18に永眠された。移植後のNEは造血幹細胞移植の合併症として比較的まれであるが,早期合併症の一つとして留意すべきである。