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『免疫抑制・化学療法により発症するB型肝炎対策のガイドライン』は徹底されているか

電子書籍販売価格(税込):
1,100

商品コード:
11092_13
著者:
中谷 綾、林 美奈、新田 祐子、中村 孝人、山東 剛裕、鎌田喜代志、辰巳 満俊
出版社:
癌と化学療法社 出版社HP
発行:
2014年
ページ数:
3ペ-ジ
ファイル容量:
1.14MB


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3台(購入日より1年間ダウンロードが可能)


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内容紹介

Are the Japanese Guidelines for the Management of Hepatitis B Virus Reactivation Being Properly Implemented ?

Summary
 Hepatitis B virus(HBV)reactivation has been reported as a fatal complication following systemic chemotherapy or other immunosuppressive therapies. The Japanese Guidelines for HBV reactivation were published in 2009. Despite the publication of these guidelines, there have been some reports of fulminant hepatitis B. Therefore, it was suggested that the guidelines were not yet been widely implemented. We investigated whether the guidelines had been implemented in our hospital. After the evaluation, it was determined that 89% of HBV cases were screened for the HBV surface antigen(HBs-Ag). Additionally, the screening for HBV surface antibody(HBs-Ab)and HBV core antibody(HBc-Ab)should be performed in cases negative for HBs-Ag, which was performed in only 17% of HBs-Ag-negative cases. It was concluded that the guidelines had not been implemented in our hospital. Therefore, we conducted educational activities to promote the implementation of the guidelines. Screening tests were performed in all 270 HBV cases between January and June 2013. Two antigen-positive carriers were identified. The rate of HBs-Ag-negative and/or HBc antibody-positive cases was 20.3%. Of these, 76.4% were tested using a DNA quantitative test, but DNA quantification did not increase in any case. HBV reactivation is expected to increase due to the development of new drugs and the use of diverse regimens. All physicians who perform immunotherapy and chemotherapy should immediately participate in educational activities.

目次

癌と化学療法 TOPへ
癌と化学療法 41巻4号 2014年4月号トップへ

【医事】

▶『免疫抑制・化学療法により発症するB型肝炎対策のガイドライン』は徹底されているか…中 谷  綾ほか

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