内容紹介
Onodera's Prognostic Nutritional Index(PNI)and the Modified Glasgow Prognostic Score(mGPS)in Colorectal Cancer Surgery
Summary
We evaluated the significance of the prognostic nutritional index(PNI)and modified Glasgow Prognostic Score(mGPS)in colorectal cancer resection. Methods: We classified 165 patients undergoing colorectal cancer excision according to PNI(>40[n=141]and ≤40[n=24])and mGPS(A/B[n=95], C[n=44], and D[n=26]). We examined the incidence of postoperative complications, postoperative hospital stay, and survival. Results: Both indices were associated with all complications, surgical site infection(SSI), and median postoperative hospital stay. RI was only associated with the mGPS, whereas a long postoperative hospital stay was associated with the PNI alone. Both indices showed a relationship with survival for each clinical stage. Conclusion: Both PNI and mGPS were useful clinical indices for patients undergoing colorectal cancer resection.
要旨
大腸癌手術症例における小野寺式栄養指数(PNI)とmodified Glasgow prognostic score(mGPS)の意義につき,術後経過との関連から比較検討した。対象と方法: 大腸癌切除165例を,PNIは>40(141例),≦40(24例),mGPSはA/B群(95例),C群(44例),D群(26例)に大別し,術後合併症(GradeⅡ以上)の発生率と術後在院日数(中央値と長期滞在例),臨床病期別生存率との関連を検討した。結果: 全合併症,SSIでは両指標,RIではGPSのみ有意な関連がみられた。術後在院日数は中央値で両指標,長期例はPNI,生存率では両指標で有意な関連がみられた。結論: PNIおよびmGPSは術後経過を反映する有用な指標と考えられた。
目次
Summary
We evaluated the significance of the prognostic nutritional index(PNI)and modified Glasgow Prognostic Score(mGPS)in colorectal cancer resection. Methods: We classified 165 patients undergoing colorectal cancer excision according to PNI(>40[n=141]and ≤40[n=24])and mGPS(A/B[n=95], C[n=44], and D[n=26]). We examined the incidence of postoperative complications, postoperative hospital stay, and survival. Results: Both indices were associated with all complications, surgical site infection(SSI), and median postoperative hospital stay. RI was only associated with the mGPS, whereas a long postoperative hospital stay was associated with the PNI alone. Both indices showed a relationship with survival for each clinical stage. Conclusion: Both PNI and mGPS were useful clinical indices for patients undergoing colorectal cancer resection.
要旨
大腸癌手術症例における小野寺式栄養指数(PNI)とmodified Glasgow prognostic score(mGPS)の意義につき,術後経過との関連から比較検討した。対象と方法: 大腸癌切除165例を,PNIは>40(141例),≦40(24例),mGPSはA/B群(95例),C群(44例),D群(26例)に大別し,術後合併症(GradeⅡ以上)の発生率と術後在院日数(中央値と長期滞在例),臨床病期別生存率との関連を検討した。結果: 全合併症,SSIでは両指標,RIではGPSのみ有意な関連がみられた。術後在院日数は中央値で両指標,長期例はPNI,生存率では両指標で有意な関連がみられた。結論: PNIおよびmGPSは術後経過を反映する有用な指標と考えられた。