内容紹介
Three Cases of Esophageal Carcinoma Achieved a Pathological Complete Response after Neoadjuvant Chemotherapy with Cisplatin and 5-Fluorouracil
Summary
We report three cases of esophageal carcinoma all of which achieved a pathological complete response after neoadjuvant chemotherapy(NAC)with cisplatin and 5-fluorouracil(CF). All three patients were men with clinical stageⅡ squamous cell carcinoma of the middle thoracic esophagus. We administered 2 courses of CF treatment as NAC and then performed radical esophagectomy. Pathologic examination revealed no viable tumor cells in the resected esophagus. The patients are currently alive with no evidence of disease.
要旨
術前CDDP/5-FU(CF)療法にて組織学的完全奏効(pathological complete response: pCR)が得られた食道癌の3例を経験した。全例男性,胸部中部食道,臨床病期Ⅱの扁平上皮癌であった。3例とも標準的CF療法を2コース施行後,根治的食道切除,3領域リンパ節郭清を施行した。切除標本に癌細胞の遺残は認められず,pCRと判定された。現在3例ともに無再発生存中である。
目次
Summary
We report three cases of esophageal carcinoma all of which achieved a pathological complete response after neoadjuvant chemotherapy(NAC)with cisplatin and 5-fluorouracil(CF). All three patients were men with clinical stageⅡ squamous cell carcinoma of the middle thoracic esophagus. We administered 2 courses of CF treatment as NAC and then performed radical esophagectomy. Pathologic examination revealed no viable tumor cells in the resected esophagus. The patients are currently alive with no evidence of disease.
要旨
術前CDDP/5-FU(CF)療法にて組織学的完全奏効(pathological complete response: pCR)が得られた食道癌の3例を経験した。全例男性,胸部中部食道,臨床病期Ⅱの扁平上皮癌であった。3例とも標準的CF療法を2コース施行後,根治的食道切除,3領域リンパ節郭清を施行した。切除標本に癌細胞の遺残は認められず,pCRと判定された。現在3例ともに無再発生存中である。