内容紹介
A Case Report of Successful Treatment for Rectosigmoid Cancer with Peritoneal Dissemination after Neoadjuvant Chemoradiotherapy with XELOX and Bevacizumab
Summary
A 60-year-old woman underwent emergency operation for ileus due to rectosigmoid cancer. Intraoperative cytology and peritoneal dissemination were positive. After performing sigmoid colostomy, she underwent neoadjuvant radiation therapy(40 Gy)and eight courses of a XELOX and bevacizumab regimen. FDG-PET did not indicate FDG accumulation after chemoradiotherapy, thus, we performed low anterior resection. Peritoneal dissemination and washing cytology were negative in the second operation. Neoadjuvant chemoradiotherapy with XELOX and bevacizumab were useful for down staging in patients with advanced colorectal cancer.
要旨
症例は60歳,女性。全周性の直腸S状部癌によるイレウスで手術を施行したが,腹水細胞診および腹膜播種陽性であった。S状結腸人工肛門造設術後,放射線療法(合計40 Gy)とXELOX+bevacizumab療法を8コース施行した。放射線化学療法後のFDG-PETで異常集積は指摘されなかった。S状結腸切除術を施行したが術中所見で腹膜播種はなく,洗浄細胞診も陰性であった。XELOX+bevacizumab療法および放射線療法は,進行結腸直腸癌に対してdown stagingを可能とする有用な治療方法と考えられた。
目次
Summary
A 60-year-old woman underwent emergency operation for ileus due to rectosigmoid cancer. Intraoperative cytology and peritoneal dissemination were positive. After performing sigmoid colostomy, she underwent neoadjuvant radiation therapy(40 Gy)and eight courses of a XELOX and bevacizumab regimen. FDG-PET did not indicate FDG accumulation after chemoradiotherapy, thus, we performed low anterior resection. Peritoneal dissemination and washing cytology were negative in the second operation. Neoadjuvant chemoradiotherapy with XELOX and bevacizumab were useful for down staging in patients with advanced colorectal cancer.
要旨
症例は60歳,女性。全周性の直腸S状部癌によるイレウスで手術を施行したが,腹水細胞診および腹膜播種陽性であった。S状結腸人工肛門造設術後,放射線療法(合計40 Gy)とXELOX+bevacizumab療法を8コース施行した。放射線化学療法後のFDG-PETで異常集積は指摘されなかった。S状結腸切除術を施行したが術中所見で腹膜播種はなく,洗浄細胞診も陰性であった。XELOX+bevacizumab療法および放射線療法は,進行結腸直腸癌に対してdown stagingを可能とする有用な治療方法と考えられた。