内容紹介
A Case of Late Recurrent Breast Cancer That Responded to Radiation Therapy and Cisplatin plus Pemetrexed Therapy
Summary
The patient was a 62-year-old woman who had undergone modified radical mastectomy for right breast cancer 19 years before. She was examined at our hospital for cough and hoarseness. After PET-CT and bronchoscopy, she was diagnosed with stageⅢB non-small cell lung cancer. Radiation therapy and cisplatin plus pemetrexed therapy were effective, and she made a recovery from a life-threatening conditon. During observation, a skin nodule was noticed on her right chest wall, and excisional biopsy revealed a skin metastasis from breast cancer. A transbronchial lung biopsy(TBLB)specimen was reexamined, and the lung lesion was shown to be metastasis from breast cancer. By changing to endocrine therapy, the disease has been effectively controlled.
要旨
症例は62歳,女性。右乳癌術後19年経過し,咳嗽,嗄声の出現があり当院を受診した。PET-CTと気管支鏡検査を施行し,右非小細胞肺癌StageⅢBと診断した。放射線療法とシスプラチン+ペメトレキセート併用療法が奏効し,生命を脅かす状態から改善した。経過観察中に右前胸部に皮膚結節を認め,切除生検を行い乳癌の皮膚転移と診断した。再度経気管支肺生検(transbronchial lung biopsy: TBLB)の検体を検討した結果,一連の病変は乳癌の転移と診断した。引き続き内分泌療法を行い,再燃なく奏効している。
目次
Summary
The patient was a 62-year-old woman who had undergone modified radical mastectomy for right breast cancer 19 years before. She was examined at our hospital for cough and hoarseness. After PET-CT and bronchoscopy, she was diagnosed with stageⅢB non-small cell lung cancer. Radiation therapy and cisplatin plus pemetrexed therapy were effective, and she made a recovery from a life-threatening conditon. During observation, a skin nodule was noticed on her right chest wall, and excisional biopsy revealed a skin metastasis from breast cancer. A transbronchial lung biopsy(TBLB)specimen was reexamined, and the lung lesion was shown to be metastasis from breast cancer. By changing to endocrine therapy, the disease has been effectively controlled.
要旨
症例は62歳,女性。右乳癌術後19年経過し,咳嗽,嗄声の出現があり当院を受診した。PET-CTと気管支鏡検査を施行し,右非小細胞肺癌StageⅢBと診断した。放射線療法とシスプラチン+ペメトレキセート併用療法が奏効し,生命を脅かす状態から改善した。経過観察中に右前胸部に皮膚結節を認め,切除生検を行い乳癌の皮膚転移と診断した。再度経気管支肺生検(transbronchial lung biopsy: TBLB)の検体を検討した結果,一連の病変は乳癌の転移と診断した。引き続き内分泌療法を行い,再燃なく奏効している。