内容紹介
A Case of a 91-Year-Old Patient with Advanced Squamous Cell Lung Cancer Complicated with Renal Dysfunction Successfully Treated with Trans-Arterial Chemo-Embolization
Summary
In 2009, a 91-year-old man with renal dysfunction was detected with a small nodule in the left pulmonary field. The nodule was found to have gradually increased in size by April, 2010. A trans-bronchial lung biopsy(TBLB)and computed tomography(CT)revealed squamous cell lung cancer and stage Ⅳ (a tumor was found on the right side as well), respectively. Systemic chemotherapy was not administered because of the advanced age of the patient and mild renal dysfunction. We obtained informed consent from the patient and his family before trans-arterial chemo-embolization(TACE)was performed. No side effects were observed either during or after treatment. Although his visits to our hospital stopped, he sought treatment for a cold 8 months after TACE. CT showed 87% shrinkage of the tumor shadow. This method could be a new therapeutic option for non-small cell lung cancer with little side effects, particularly in older patients or those with pulmonary complications.
要旨 症例は腎障害合併の91歳,男性。2009年に左肺野に小腫瘤影を指摘されたが放置。腫瘤は徐々に増大し2010年4月にTBLBとCTから肺扁平上皮癌で,病期は右肺腫瘍の存在からstage Ⅳ期と診断した。全身化学療法は高齢で軽度腎障害がみられることから施行せず。われわれは,同意を得た後に抗癌剤量が少ない経動脈的抗癌剤動注-塞栓療法(TACE)を施行したが治療中やその後において副作用は観察されなかった。患者は通院しなくなったものの8か月後に感冒治療にて来院され,その際のCTで腫瘍は87%縮小していた。この方法は,高齢者や肺合併症を有する非小細胞肺癌症例に対し副作用の少ない新しい治療法となるかもしれない。
目次
Summary
In 2009, a 91-year-old man with renal dysfunction was detected with a small nodule in the left pulmonary field. The nodule was found to have gradually increased in size by April, 2010. A trans-bronchial lung biopsy(TBLB)and computed tomography(CT)revealed squamous cell lung cancer and stage Ⅳ (a tumor was found on the right side as well), respectively. Systemic chemotherapy was not administered because of the advanced age of the patient and mild renal dysfunction. We obtained informed consent from the patient and his family before trans-arterial chemo-embolization(TACE)was performed. No side effects were observed either during or after treatment. Although his visits to our hospital stopped, he sought treatment for a cold 8 months after TACE. CT showed 87% shrinkage of the tumor shadow. This method could be a new therapeutic option for non-small cell lung cancer with little side effects, particularly in older patients or those with pulmonary complications.
要旨 症例は腎障害合併の91歳,男性。2009年に左肺野に小腫瘤影を指摘されたが放置。腫瘤は徐々に増大し2010年4月にTBLBとCTから肺扁平上皮癌で,病期は右肺腫瘍の存在からstage Ⅳ期と診断した。全身化学療法は高齢で軽度腎障害がみられることから施行せず。われわれは,同意を得た後に抗癌剤量が少ない経動脈的抗癌剤動注-塞栓療法(TACE)を施行したが治療中やその後において副作用は観察されなかった。患者は通院しなくなったものの8か月後に感冒治療にて来院され,その際のCTで腫瘍は87%縮小していた。この方法は,高齢者や肺合併症を有する非小細胞肺癌症例に対し副作用の少ない新しい治療法となるかもしれない。