内容紹介
A Case of Advanced Gastric Cancer with Regional Lymph Node Metastasis Showing Pathological Complete Response after Preoperative Chemotherapy with Docetaxel, Cisplatin, and S-1
Summary
A 64-year-old man was diagnosed with advanced gastric cancer type 3 and regional celiac trunk lymph node metastases. We performed preoperative chemotherapy with docetaxel, cisplatin, and S-1(DCS therapy). Total gastrectomy with lymph node dissection was performed after 2 courses of DCS. Pathologically, no viable cells were found in the primary lesion or in the dissected lymph nodes. The pathological response to preoperative DCS therapy was classified as grade 3. The postoperative course was uneventful; the patient is currently healthy and receives periodic medical examinations.
要旨
64歳,男性。吐血を主訴に受診し,進行胃癌と診断された。精査にて,胃小弯～腹腔動脈周囲のbulkyなリンパ節転移が認められ,治療前診断は,胃癌cT4aN2M0,StageⅢBと診断した。術前化学療法として分割DCS(docetaxel+cisplatin+S-1)療法を2コース施行した。化学療法は奏効し,PRが得られた後,胃全摘術を施行した。病理学的所見では原発巣,リンパ節ともに腫瘍の残存は認められず,組織学的効果判定はGrade 3であった。術後経過は良好で,手術11か月後の現在,経過観察中である。
目次
Summary
A 64-year-old man was diagnosed with advanced gastric cancer type 3 and regional celiac trunk lymph node metastases. We performed preoperative chemotherapy with docetaxel, cisplatin, and S-1(DCS therapy). Total gastrectomy with lymph node dissection was performed after 2 courses of DCS. Pathologically, no viable cells were found in the primary lesion or in the dissected lymph nodes. The pathological response to preoperative DCS therapy was classified as grade 3. The postoperative course was uneventful; the patient is currently healthy and receives periodic medical examinations.
要旨
64歳,男性。吐血を主訴に受診し,進行胃癌と診断された。精査にて,胃小弯～腹腔動脈周囲のbulkyなリンパ節転移が認められ,治療前診断は,胃癌cT4aN2M0,StageⅢBと診断した。術前化学療法として分割DCS(docetaxel+cisplatin+S-1)療法を2コース施行した。化学療法は奏効し,PRが得られた後,胃全摘術を施行した。病理学的所見では原発巣,リンパ節ともに腫瘍の残存は認められず,組織学的効果判定はGrade 3であった。術後経過は良好で,手術11か月後の現在,経過観察中である。