内容紹介
Analysis of the Side Effects of Docetaxel with Cyclophosphamide(TC Therapy)
Summary
The effectiveness of TC therapy, a non-anthracycline regimen, was determined through the US Oncology 9735 trial, which was conducted overseas. This led to high expectations regarding the use of TC therapy as a postoperative adjuvant treatment for early-stage breast cancer. We studied 38 patients with breast cancer who underwent TC treatment in our department between August 2008 and November 2009, and discussed the development of side effects in the patients. Continuation of TC therapy on an outpatient basis was considered possible if exanthema and edema were adequately managed.
要旨
海外ではUS Oncology 9735試験が実施され,非anthracycline系レジメンであるTC療法(docetaxel+cyclophosphamide)の有用性が示されたことにより,早期乳癌に対する術後補助療法としてTC療法に対する期待は大きい。2008年8月～2009年11月までに当科にてTC療法を施行した乳癌患者38例を評価対象とし,副作用発現に関して検討した。TC療法は皮疹,浮腫に対する適切なマネージメントができれば外来にて継続可能な治療と考えられた。
目次
Summary
The effectiveness of TC therapy, a non-anthracycline regimen, was determined through the US Oncology 9735 trial, which was conducted overseas. This led to high expectations regarding the use of TC therapy as a postoperative adjuvant treatment for early-stage breast cancer. We studied 38 patients with breast cancer who underwent TC treatment in our department between August 2008 and November 2009, and discussed the development of side effects in the patients. Continuation of TC therapy on an outpatient basis was considered possible if exanthema and edema were adequately managed.
要旨
海外ではUS Oncology 9735試験が実施され,非anthracycline系レジメンであるTC療法(docetaxel+cyclophosphamide)の有用性が示されたことにより,早期乳癌に対する術後補助療法としてTC療法に対する期待は大きい。2008年8月～2009年11月までに当科にてTC療法を施行した乳癌患者38例を評価対象とし,副作用発現に関して検討した。TC療法は皮疹,浮腫に対する適切なマネージメントができれば外来にて継続可能な治療と考えられた。