内容紹介
Cases of Three Patients with Gastric Cancer and Metastasis to the Skeletal Muscle
Summary
Metastasis to the skeletal muscle from gastric cancer is relatively rare. We report cases of 3 patients undergoing chemotherapy for gastric cancer with metastasis to the skeletal muscle. Case 1: A man in his 70s was diagnosed with advanced gastric cancer(cT4N3M1P0, stage Ⅳ), with metastasis to the lung, brain, lymph node, and iliopsoas muscle. Case 2: A man in his 60s was diagnosed with advanced gastric cancer(cT3N3M1P0, stage Ⅳ), with metastasis to the brain, lung, lymph node, and iliopsoas muscle. Case 3: A man in his 50s was diagnosed with advanced gastric cancer(cT4N3M1P0, stage Ⅳ), with metastasis to the urinary duct, lymph node, back muscle, and iliopsoas muscle. All 3 patients died within 7-8 months after the diagnosis due to progressive disease despite chemotherapy. The prognosis of these 3 patients was significantly poorer than that of patients in our hospital with metastasis not involving the skeletal muscle(p<0.01). Accordingly, metastasis to the skeletal muscle may be an adverse prognostic factor in gastric cancer.
要旨
当院で化学療法を行った切除不能進行胃癌のうち,骨格筋転移を来した症例について報告する。症例1は70歳台,男性。造影CT検査にて肺転移,多発リンパ節転移,脳転移に加えて腸腰筋転移を認めた。症例2は60歳台,男性。造影CT検査にて肺転移,リンパ節転移,腸腰筋転移を認めた。症例3は50歳台,男性。造影CT検査にて多発リンパ節転移に加えて尿管浸潤,腹膜転移,腸腰筋・臀筋・背筋に転移を認めた。3症例とも全身化学療法を施行するも,初診より7～8か月で永眠された。これらは,当院での骨格筋転移を有さない他臓器転移症例と比較して有意に予後不良であった(p<0.01)。胃癌の骨格筋転移は転移形式として比較的まれであるが,化学療法無効例が多く予後不良因子の一つと考えられた。
目次
Summary
Metastasis to the skeletal muscle from gastric cancer is relatively rare. We report cases of 3 patients undergoing chemotherapy for gastric cancer with metastasis to the skeletal muscle. Case 1: A man in his 70s was diagnosed with advanced gastric cancer(cT4N3M1P0, stage Ⅳ), with metastasis to the lung, brain, lymph node, and iliopsoas muscle. Case 2: A man in his 60s was diagnosed with advanced gastric cancer(cT3N3M1P0, stage Ⅳ), with metastasis to the brain, lung, lymph node, and iliopsoas muscle. Case 3: A man in his 50s was diagnosed with advanced gastric cancer(cT4N3M1P0, stage Ⅳ), with metastasis to the urinary duct, lymph node, back muscle, and iliopsoas muscle. All 3 patients died within 7-8 months after the diagnosis due to progressive disease despite chemotherapy. The prognosis of these 3 patients was significantly poorer than that of patients in our hospital with metastasis not involving the skeletal muscle(p<0.01). Accordingly, metastasis to the skeletal muscle may be an adverse prognostic factor in gastric cancer.
要旨
当院で化学療法を行った切除不能進行胃癌のうち,骨格筋転移を来した症例について報告する。症例1は70歳台,男性。造影CT検査にて肺転移,多発リンパ節転移,脳転移に加えて腸腰筋転移を認めた。症例2は60歳台,男性。造影CT検査にて肺転移,リンパ節転移,腸腰筋転移を認めた。症例3は50歳台,男性。造影CT検査にて多発リンパ節転移に加えて尿管浸潤,腹膜転移,腸腰筋・臀筋・背筋に転移を認めた。3症例とも全身化学療法を施行するも,初診より7～8か月で永眠された。これらは,当院での骨格筋転移を有さない他臓器転移症例と比較して有意に予後不良であった(p<0.01)。胃癌の骨格筋転移は転移形式として比較的まれであるが,化学療法無効例が多く予後不良因子の一つと考えられた。